Lactobacillus Research Today is a free monthly online journal that collates and summarizes the latest research about Lactobacillus, including details on probiotics, digestion, diet, health, lactobacillus acidophilus.

Antagonistic activity against Salmonella infection in vitro and in vivo for two Lactobacillus strains from swine and poultry.

Tsai CC, Hsih HY, Chiu HH, Lai YY, Liu JH, Yu B, Tsen HY

Department of Food Science, National Chung-Hsing University, Taichung, Taiwan, R.O.C.

In this study, we isolated two lactobacillus strains, i.e., strain LAP5 and LF33, from swine and poultry, respectively, and showed that both strains were acid as well as bile tolerant and were able to adhere to the cultured human intestinal cell lines, such as Int-407 and Caco-2 cells, and to the intestinal epithelium cells isolated from swine, poultry and mouse (BALB/c). Both of these LAB strains were shown to inhibit the growth of Escherichia coli, Salmonella typhimurium, Staphylococcus aureus and Bacillus cereus. When these two LAB strains were evaluated for their antagonistic activity against Salmonella (S. typhimurium) invasion to cultured human intestinal cell line Int-407 and to mouse (BALB/c) liver and spleen, these two LAB strains were found to have significant antagonistic effect.

Published 4 July 2005 in Int J Food Microbiol, 102(2): 185-94.
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